Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.

@article{Son2015InductionOI,
  title={Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.},
  author={G Y Son and Jeong Hee Hong and Inik Chang and Dong Min Shin},
  journal={Archives of oral biology},
  year={2015},
  volume={60 4},
  pages={526-32}
}
OBJECTIVE The oral cavity is often exposed to not only diverse external pathogens but also dramatic temperature changes. In this study, we investigated the effect of thermal stress on PDL cells with a focus on the inflammatory responses and bone homeostasis. DESIGN The PDL cells were isolated from healthy premolar extracted for orthodontic reasons, and examined using intracellular calcium concentration ([Ca(2+)]i) measurement and reverse transcription-polymerase chain reaction for pro… CONTINUE READING
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