Induction of Extrahepatic Biliary Carcinoma by N‐Nitrosobis(2‐oxopropyl)amine in Hamsters Given Cholecystoduodenostomy with Dissection of the Common Duct


The methods we used to produce a carcinoma in the extrahepatic bile duct and gallbladder in hamsters are described along with the characteristics of the induced tumors. Female Syrian golden hamsters were first subjected to cholecystoduodenostomy with dissection of the extrahepatic bile duct on the distal end of the common duct (CDDB) and were, 4 weeks later… (More)

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