• Corpus ID: 11329995

Induction of Difterentiation in Human Promyelocytic Cell Line HL60 by a New Type of Polyenes, Falconensone A and Its Derivatives Leukemia

@inproceedings{Takahashi1998InductionOD,
  title={Induction of Difterentiation in Human Promyelocytic Cell Line HL60 by a New Type of Polyenes, Falconensone A and Its Derivatives Leukemia},
  author={Noriko Takahashi and Ken-ichi Kawai and Tetsuya Fukui},
  year={1998}
}
Falconensones A and B are new type of yellow pigment isolated from the mycelial extract of ascolnycetous fungi, Emericella faiconensis or Emericella /~uticulosa~ whose structures are similar to retinoic acid (RA). To date, biological activities of falconensones have not been reported. Herein, we reported that falconensone A inhibited growih of HL60 human lenkemia cells, when used either singly or in combination with RA Falconensone A alone did not induce differentiation of HL60 cells. However… 

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