Induction of DNA strand breakage and apoptosis in the eel Anguilla anguilla.

  title={Induction of DNA strand breakage and apoptosis in the eel Anguilla anguilla.},
  author={Marco Nigro and Giada Frenzilli and Vittoria Scarcelli and Stefania Gorbi and Francesco Regoli},
  journal={Marine environmental research},
  volume={54 3-5},
The ability of benzo[a]pyrene, Aroclor 1254, 2-3-7-8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone to induce DNA strand breaks (SB) and apoptosis in erythrocytes of the European eel (Anguilla anguilla) was investigated following by in vivo exposure. DNA damage was evaluated by the Comet assay, while the diffusion assay was used to investigate the induction of apoptosis 7 days after a single intraperitoneal administration. 2-3-7-8-Tetrachlorodibenzo-p-dioxin induced the highest genotoxic… CONTINUE READING


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