Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

  title={Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination},
  author={Chih-Jen Wei and Jeffrey C. Boyington and Patrick M. McTamney and Wing-Pui Kong and Melissa B. Pearce and Ling Xu and Hanne Andersen and Srinivas S. Rao and Terrence M. Tumpey and Zhi-yong Yang and Gary J. Nabel},
  pages={1060 - 1064}
Toward a General Flu Vaccination Current seasonal influenza virus vaccines are targeted against specific viral strains and do not provide broad, durable protection. Seasonal influenza vaccines induce protective antibody responses against regions of viral hemagglutinin (HA) that rapidly mutate so that very soon, the virus becomes resistant to vaccination. Conserved regions of HA also exist, and a major goal of influenza vaccine development is to design a vaccine that elicits antibodies against… 

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