Induction of B cell and T cell tolerance in vivo by anti-CD23 mAb.

Abstract

T cell tolerance can be induced by B cell presentation of Ags to naive T cells. To further characterize this mechanism of T cell tolerance induction, we have investigated the effects of injecting mice with an intact rat IgG2a Ab, which binds to the B cell low-affinity Fc epsilon receptor (CD23), on the responsiveness of B cells and T cells to rat IgG2a. Our… (More)

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@article{Morris1994InductionOB, title={Induction of B cell and T cell tolerance in vivo by anti-CD23 mAb.}, author={Steve Morris and A. J. Lees and Jane M Holmes and R. D. Jeffries and Fred D. Finkelman}, journal={Journal of immunology}, year={1994}, volume={152 8}, pages={3768-76} }