Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells.

@article{Sachi1995InductionOA,
  title={Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells.},
  author={Yoshifumi Sachi and Kiichi Hirota and Hiroshi Masutani and Ken-ichi Toda and Takashi Okamoto and Masahiro Takigawa and Junji Yodoi},
  journal={Immunology letters},
  year={1995},
  volume={44 2-3},
  pages={
          189-93
        }
}
Adult T-cell leukemia-derived factor (ADF)/human thioredoxin (TRX) has thiol-dependent reducing activities and is known to have regulatory roles on the DNA-protein interaction and cell activation. Inducive effect of ultraviolet (UV) has been indicated because of the enhanced expression of ADF/TRX in epidermal cells of sun-exposed skin, as determined by immunohistochemical staining with antibody against recombinant ADF (rADF). We studied the effect of UVB irradiation and other oxidative stress… CONTINUE READING
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