Induction kinetics of a conditional pH stress response system in Escherichia coli.

@article{Fritz2009InductionKO,
  title={Induction kinetics of a conditional pH stress response system in Escherichia coli.},
  author={Georg Fritz and Christiane M Koller and Korinna Burdack and Larissa Tetsch and Ina Haneburger and Kirsten Jung and Ulrich Gerland},
  journal={Journal of molecular biology},
  year={2009},
  volume={393 2},
  pages={272-86}
}
The analysis of stress response systems in microorganisms can reveal molecular strategies for regulatory control and adaptation. In this study, we focused on the Cad module, a subsystem of Escherichia coli's response to acidic stress that is conditionally activated at low pH only when lysine is available. When expressed, the Cad system counteracts the elevated H(+) concentration by converting lysine to cadaverine under the consumption of H(+) and exporting cadaverine in exchange for external… CONTINUE READING

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