Induction cisplatin and fluorouracil-based chemotherapy followed by concurrent chemoradiation for muscle-invasive bladder cancer.

@article{Lin2009InductionCA,
  title={Induction cisplatin and fluorouracil-based chemotherapy followed by concurrent chemoradiation for muscle-invasive bladder cancer.},
  author={C R Lin and C. -P. Hsu and Jason Chia-Hsien Cheng and Chao-yuan Huang and Yu-Chieh Tsai and F. R. Hsu and Kuo How Huang and Ann-lii Cheng and Y K Pu},
  journal={International journal of radiation oncology, biology, physics},
  year={2009},
  volume={75 2},
  pages={442-8}
}
PURPOSE To evaluate a multimodality bladder-preserving therapy in patients with muscle-invasive bladder cancer. METHODS AND MATERIALS Patients with stages T2-4aN0M0 bladder cancer suitable for cystectomy underwent radical transurethral resection and induction chemotherapy, followed by concurrent chemoradiotherapy (CCRT). Patients with a Karnofsky performance status (KPS) <80 or age > or =70 years underwent Protocol A: induction chemotherapy with three cycles of the cisplatin and 5… CONTINUE READING

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