Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer.

@article{Schou2012InductionCW,
  title={Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer.},
  author={Jakob Vasehus Schou and Finn Ole Larsen and L. L. Rasch and Dorte Linnemann and Jesper Langhoff and Estrid V. S. H\ogdall and Dorte Lisbet Nielsen and Kirsten K Vistisen and A Fromm and Benny Vittrup Jensen},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2012},
  volume={23 10},
  pages={2627-33}
}
BACKGROUND Preoperative chemoradiation in patients with locally advanced rectal cancer has no impact on overall survival (OS) and distant recurrences. The aim of the study was to evaluate local downstaging, toxicity and long-term outcome in patients with locally advanced rectal cancer after induction therapy with capecitabine and oxaliplatin (CAPEOX) followed by radiotherapy concomitant with capecitabine [chemoradiotherapy (CRT)] before total mesorectal excision (TME). PATIENTS AND METHODS… CONTINUE READING
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Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study

  • MERCURY Study Group
  • BMJ
  • 2006
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