Induction and suppression of allergic diarrhea and systemic anaphylaxis in a murine model of food allergy.

@article{Kucuk2012InductionAS,
  title={Induction and suppression of allergic diarrhea and systemic anaphylaxis in a murine model of food allergy.},
  author={Zeynep Yesim Kucuk and Richard T. Strait and Marat V. Khodoun and Ashley M Mahler and Simon P Hogan and Fred D. Finkelman},
  journal={The Journal of allergy and clinical immunology},
  year={2012},
  volume={129 5},
  pages={1343-8}
}
BACKGROUND The clinical manifestations of food allergy include diarrhea and systemic anaphylaxis (shock), which can occur together or by themselves in different subjects. Although ingested food antigens need to be absorbed to induce shock, it is not known whether they need to be absorbed to induce diarrhea. OBJECTIVE We sought to identify mechanisms that determine whether food allergy induces diarrhea versus shock and determine whether diarrhea requires absorption of ingested antigens… CONTINUE READING