Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.

@article{Speit2000InductionAR,
  title={Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.},
  author={Guenter Speit and Petra Sch{\"u}tz and Oliver Merk},
  journal={Mutagenesis},
  year={2000},
  volume={15 1},
  pages={85-90}
}
We have previously shown that the alkaline Comet assay (single cell gel electrophoresis) in a modified version is a sensitive test for the detection of formaldehyde-induced DNA-protein crosslinks (DPC). Our results also indicated that formaldehyde-induced DPC are related to the formation of chromosomal effects such as micronuclei and sister chromatid exchanges. To better understand the genetic consequences of formaldehyde-induced DPC we have now investigated the induction and removal of DPC in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…