Induction and modulation of acute-phase response by protein malnutrition in rats: comparative effect of systemic and localized inflammation on interleukin-6 and acute-phase protein synthesis.

@article{Lyoumi1998InductionAM,
  title={Induction and modulation of acute-phase response by protein malnutrition in rats: comparative effect of systemic and localized inflammation on interleukin-6 and acute-phase protein synthesis.},
  author={Said Lyoumi and Fabienne Tamion and J F Petit and Pierre D{\'e}chelotte and Charlie Dauguet and Michel Scott{\'e} and Martine Hiron and Antony Leplingard and J P Salier and Maryvonne Daveau and J. P. Lebreton},
  journal={The Journal of nutrition},
  year={1998},
  volume={128 2},
  pages={166-74}
}
The acute-phase protein (APP) response is regulated by cytokines such as interleukin-6 (IL-6), interleukin-1 (IL-1) and tumor necrosis factor (TNF), but may also be influenced by malnutrition. The aims of this study were as follows: 1) to determine in rats the effect of a protein-deficient diet on IL-6 mRNA expression in intestine, liver and peripheral blood mononuclear cells (PBMC), and on alpha-1 acid glycoprotein (AGP) and alpha-2 macroglobulin (A2M) serum levels and hepatic mRNA expression… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…