Induction and mechanism of apoptosis by hydroxycamptothecin in human Tenon's capsule fibroblasts.

Abstract

PURPOSE We investigated apoptosis induced by hydroxycamptothecin (HCPT) in human Tenon's capsule using fibroblasts cultured from human Tenon's capsule (HTFs), and the mechanism of induction. METHODS HTFs were treated with 0-4 mg/L HCPT for 24 hours. Cell proliferation was measured by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay… (More)
DOI: 10.1167/iovs.11-8968

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