Induction and maintenance therapy with intermittent interleukin-2 in HIV-1 infection.

@article{Farel2004InductionAM,
  title={Induction and maintenance therapy with intermittent interleukin-2 in HIV-1 infection.},
  author={Claire E Farel and Doreen G. Chaitt and Barbara K. Hahn and Jorge A. Tavel and Joseph A Kovacs and Michael A. Polis and Henry Masur and Dean A Follmann and H. Clifford Lane and Richard T. Davey},
  journal={Blood},
  year={2004},
  volume={103 9},
  pages={
          3282-6
        }
}
Studies establishing that intermittent subcutaneous interleukin-2 (IL-2) therapy can lead to substantial CD4 cell increases in many HIV-infected patients have generally been of limited duration. We studied 77 patients participating in active longitudinal studies of subcutaneous IL-2 therapy at our center in order to determine the long-term feasibility of this approach. Following initial induction, patients in each trial were eligible to receive intermittent 5-day cycles of subcutaneous IL-2… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Effects of interleukin-2 plus highly active antiretroviral therapy on HIV-1 replication and proviral DNA (COSMIC trial)

  • HJ Stellbrink, J van Lunzen, M Westby
  • 2002

Prolonged and preferential survival of CD4 lymphocytes in HIV-infected patients receiving IL-2 therapy [abstract

  • JA Kovacs, R Lempicki, I Sidorov
  • Ninth Conference on Retroviruses and Opportunistic Infections. February
  • 2002

fects of interleukin - 2 plus highly active antiretroviral therapy on HIV - 1 replication and proviral DNA ( COSMIC trial )

  • HJ Stellbrink, J vanLunzen, M Westby
  • AIDS
  • 2002

Immunomodulators as adjunctive therapy for HIV-1 infection.

  • Sarah L. Pett, S. Emery
  • Medicine
  • Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
  • 2001