Induction and evasion of the type I interferon response by cytomegaloviruses.

@article{Defilippis2007InductionAE,
  title={Induction and evasion of the type I interferon response by cytomegaloviruses.},
  author={Victor R Defilippis},
  journal={Advances in experimental medicine and biology},
  year={2007},
  volume={598},
  pages={309-24}
}
Cytomegaloviruses represent supreme pathogens in that they are capable of occupying healthy mammalian hosts for life in the face of constant antiviral immune reactions. The inability of the host to eliminate the virus likely results from numerous counteractive strategies employed to disrupt the immune response. The role of type I interferon in the antiviral response has been well documented although only recently have the pathways of induction of this powerful cytokine been described… CONTINUE READING