Induction and effector functions of TH17 cells

@article{Bettelli2008InductionAE,
  title={Induction and effector functions of TH17 cells},
  author={Estelle Bettelli and Thomas Korn and Mohamed Oukka and Vijay K Kuchroo},
  journal={Nature},
  year={2008},
  volume={453},
  pages={1051-1057}
}
T helper (TH) cells constitute an important arm of the adaptive immune system because they coordinate defence against specific pathogens, and their unique cytokines and effector functions mediate different types of tissue inflammation. The recently discovered TH17 cells, the third subset of effector T helper cells, have been the subject of intense research aimed at understanding their role in immunity and disease. Here we review emerging data suggesting that TH17 cells have an important role in… CONTINUE READING
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