Induction and Inhibition of Crystallization in Drug-in-Adhesive-Type Transdermal Patches

Abstract

To screen crystallization inhibitors, perform accelerated stability testing and predict saturation solubility of levonorgestrel in drug-in-adhesive patches. Differential scanning calorimetry (DSC) studies were compared against slide crystallization studies for screening additives. Release studies were performed from crystallized and supersaturated patches… (More)
DOI: 10.1007/s11095-012-0901-7

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