Inducing nonsense suppression by targeted pseudouridylation


Isomerization from uridine to pseudouridine (pseudouridylation) is largely catalyzed by a family of small ribonucleoproteins called box H/ACA RNPs, each of which contains one unique small RNA—the box H/ACA RNA. The specificity of the pseudouridylation reaction is determined by the base-pairing interactions between the guide sequence of the box H/ACA RNA and… (More)
DOI: 10.1038/nprot.2012.029


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@article{Huang2012InducingNS, title={Inducing nonsense suppression by targeted pseudouridylation}, author={Chao Huang and Guowei Wu and Yi-Tao Yu}, journal={Nature Protocols}, year={2012}, volume={7}, pages={789-800} }