Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids

@inproceedings{Knight2010InducingCP,
  title={Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids},
  author={Emilie Knight and Emma Greer and Tracie Draeger and Vera Thole and Steve Reader and Peter J. Shaw and Graham Moore},
  booktitle={Functional & Integrative Genomics},
  year={2010}
}
At the onset of meiosis, chromosomes first decondense and then condense as the process of recognition and intimate pairing occurs between homologous chromosomes. We show here that okadaic acid, a drug known to induce chromosome condensation, can be introduced into wheat interspecific hybrids prior to meiosis to induce chromosome pairing. This pairing occurs in the presence of the Ph1 locus, which usually suppresses pairing of related chromosomes and which we show here delays condensation. Thus… CONTINUE READING