Inducible virus-mediated expression of a foreign protein in suspension-cultured plant cells

  title={Inducible virus-mediated expression of a foreign protein in suspension-cultured plant cells},
  author={Koji Dohi and Masaki Nishikiori and Atsushi Tamai and Masayuki Ishikawa and Tetsuo Meshi and Masasi Mori},
  journal={Archives of Virology},
Although suspension-cultured plant cells have many potential merits as sources of useful proteins, the lack of an efficient expression system has prevented using this approach. In this study, we established an inducible tomato mosaic virus (ToMV) infection system in tobacco BY-2 suspension-cultured cells to inducibly and efficiently produce a foreign protein. In this system, a modified ToMV encoding a foreign protein as replacement of the coat protein is expressed from stably transformed cDNA… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 24 extracted citations

Plant Viral Vectors

Current Topics in Microbiology and Immunology • 2014

Plant viral vectors for delivery by Agrobacterium.

Current topics in microbiology and immunology • 2014
View 1 Excerpt

Hairy roots as a vaccine production and delivery system.

Advances in biochemical engineering/biotechnology • 2013
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 30 references

Stable expression of human beta1,4-galactosyltransferase in plant cells modifies N-linked glycosylation patterns.

Proceedings of the National Academy of Sciences of the United States of America • 1999
View 8 Excerpts
Highly Influenced

Tobacco BY-2 cell line as the “HeLa” cell in the cell biology of higher plants

T Nagata, Y Nemoto, S Hasezawa
Int Rev Cytol • 1992
View 4 Excerpts
Highly Influenced

Expression of a

KL Hefferon, Y Fan
VACCINE • 2004

protein in a plant cell line using a geminivirus - based replicon system

S Hellwig, J Drossard, RM Twyman, R Fischer

Similar Papers

Loading similar papers…