Inducible nitric oxide synthase inhibition delays death of rabies virus-infected mice.

@article{Ubol2001InducibleNO,
  title={Inducible nitric oxide synthase inhibition delays death of rabies virus-infected mice.},
  author={Sukathida Ubol and C Sukwattanapan and Yaowapa Maneerat},
  journal={Journal of medical microbiology},
  year={2001},
  volume={50 3},
  pages={238-42}
}
A pathophysiological mechanism of cerebral damage and impairment of neuronal function during rabies virus infection was examined. Synthesis of nitric oxide (NO) and expression of the inducible nitric oxide synthase (iNOS) gene are strongly upregulated during rabies virus infection. Treatment of rabies virus-infected mice with a selective inhibitor of iNOS… CONTINUE READING