Inducible nitric oxide synthase in monocytes from patients with Graves' disease.

@article{LpezMoratalla1996InducibleNO,
  title={Inducible nitric oxide synthase in monocytes from patients with Graves' disease.},
  author={Natalia L{\'o}pez-Moratalla and Anne Calleja and Adriana Vilchis Gonzalez and L Alberto Perez-Mediavilla and Mar{\'i}a S. Aymerich and Marta Burrel and Esteban Santiago},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={226 3},
  pages={723-9}
}
The presence of inducible nitric oxide synthase (iNOS) in fresh monocytes from patients with Graves' disease was demonstrated for the first time. Immunophenotypic analysis showed a profile reflecting a state of activation and differentiation of monocytes. Incubation of lymphomononuclear cells from healthy volunteers in the presence of synthetic peptides with sequences related to thyroid autoantigens (TSH receptor, thyroid peroxidase, or thyroglobulin) led to a stimulation of monocytes… CONTINUE READING