Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms

@inproceedings{Alekseeva2008InducibleEO,
  title={Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms},
  author={Ludmila Alekseeva and Dominique Huet and Françoise F{\'e}m{\'e}nia and Isabelle Mouyna and Mahdia Abdelouahab and Adrien Cagna and Daniel Guerrier and Virginie Tichann{\'e}-Seltzer and Armelle Baeza-Squiban and Ren{\'e} Chermette and J. P. Latg{\'e} and Nadia Berkova},
  booktitle={BMC Microbiology},
  year={2008}
}
Aspergillus fumigatus, a saprophytic mould, is responsible for life-threatening, invasive pulmonary diseases in immunocompromised hosts. The role of the airway epithelium involves a complex interaction with the inhaled pathogen. Antimicrobial peptides with direct antifungal and chemotactic activities may boost antifungal immune response. The inducible expression of defensins by human bronchial epithelial 16HBE cells and A549 pneumocyte cells exposed to A. fumigatus was investigated. Using RT… CONTINUE READING

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