Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.

  title={Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.},
  author={D Inoue and Hiroshi Kubo and Keiko Taguchi and Takashi Suzuki and M. Asaliaru Komatsu and Hozumi Motohashi and Masayuki Yamamoto},
  journal={Biochemical and biophysical research communications},
  volume={405 1},
Autophagy is a highly conserved process primarily known for its role in cellular adaptation to nutritional stress. This bulk protein degradation pathway relocates nutrients during starvation. Recent studies, however, have revealed essential roles of autophagy in various organs under normal conditions. Especially, autophagy is now recognized as the pathway responsible for the elimination of damaged proteins resulting from environmental stress. Lungs are constantly exposed to high oxygen tension… CONTINUE READING
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