Inducible capillary formation in lymphatic endothelial cells by blocking lipid phosphate phosphatase-3 activity.

@article{Senda2009InducibleCF,
  title={Inducible capillary formation in lymphatic endothelial cells by blocking lipid phosphate phosphatase-3 activity.},
  author={Kazutaka Senda and Keiichi Koizumi and Orawin Prangsaengtong and Takayuki Minami and Shunsuke Suzuki and Ichiro Takasaki and Yoshiaki Tabuchi and Hiroaki Sakurai and Yoshinori Doki and Takuro Misaki and Ikuo Saiki},
  journal={Lymphatic research and biology},
  year={2009},
  volume={7 2},
  pages={69-74}
}
Lymphangiogenesis plays critical roles under normal and/or pathological conditions; however, the molecular contributors to this event were unknown until recently. In the present study, we first employed gene chip analysis and confirmed that lipid phosphate phosphatase-3 (LPP3) expression was increased until capillary formation in the conditionally immortalized rat lymphatic endothelial cell line. Signaling responses occur when several lipids induce acute biological functions; further, lipid… CONTINUE READING