Inducible binding of a factor to the c-fos regulatory region.

@article{Hayes1987InducibleBO,
  title={Inducible binding of a factor to the c-fos regulatory region.},
  author={Timothy E. Hayes and Ann M. Kitchen and Brent H Cochran},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 5},
  pages={1272-6}
}
The c-fos gene is rapidly and transiently activated in quiescent BALB/c-3T3 cells in response to serum, platelet-derived growth factor or conditioned medium from v-sis-transformed cells. This activation occurs at the level of transcription and in the absence of new protein synthesis. Using a gel electrophoresis DNA-binding assay, we have found a DNA-binding activity in BALB/c-3T3 cells that is induced within 20 min of treatment with conditioned medium from v-sis-transformed cells. A DNA… CONTINUE READING
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