Inducible bacteriocin production in Lactobacillus is regulated by differential expression of the pln operons and by two antagonizing response regulators, the activity of which is enhanced upon phosphorylation.

@article{Diep2003InducibleBP,
  title={Inducible bacteriocin production in Lactobacillus is regulated by differential expression of the pln operons and by two antagonizing response regulators, the activity of which is enhanced upon phosphorylation.},
  author={Dzung Bao Diep and Ronny Myhre and Ola Johnsborg and {\AA}got Aakra and Ingolf F. Nes},
  journal={Molecular microbiology},
  year={2003},
  volume={47 2},
  pages={483-94}
}
Expression of the five (pln) operons involved in the bacteriocin production of Lactobacillus plantarum C11 is regulated by a so-called pheromone-based signal-transducing network, in which the peptide pheromone (PlnA) induces bacteriocin production through the action of a histidine protein kinase (PlnB) and two antagonizing response regulators (PlnC as an activator and PlnD as a negative regulator). All pln-regulated promoters contain a conserved pair of direct repeats that serve as binding… CONTINUE READING

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