Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue.


OBJECTIVE Inflammatory activity in fat tissue has recently been implicated in mechanisms of insulin resistance and obesity-related metabolic dysfunction. Toll-like receptors (TLRs) play a key role in innate immune responses and recent studies implicate the TLR pathway in mechanisms of inflammation and atherosclerosis. The aim of this study was to examine… (More)
DOI: 10.1038/oby.2008.25


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