Inducible Rubicon facilitates viral replication by antagonizing interferon production

Abstract

The RUN domain Beclin-1-interacting cysteine-rich-containing (Rubicon) protein is involved in the maturation step of autophagy and the endocytic pathway as a Beclin-1-binding partner, but little is known regarding the role of Rubicon during viral infection. Here, we performed functional studies of the identified target in interferon (IFN) signaling pathways… (More)
DOI: 10.1038/cmi.2017.1

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