Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism.

@article{Widlak2007Inducible7K,
  title={Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism.},
  author={Wieslawa Widlak and Boleslaw K. Winiarski and Aleksandra Ewa Krawczyk and Natalia Vydra and Ewa Malusecka and Z. Krawczyk},
  journal={International journal of andrology},
  year={2007},
  volume={30 2},
  pages={
          80-7
        }
}
Accumulation of inducible heat shock proteins (e.g. Hsp70i) during cellular stress confers thermotolerance, reduces the consequences of damage and facilitates cellular recovery, while abrogation of Hsp70i expression renders sensitivity to apoptosis. Testis translocation into abdominal cavity, which results in temperature elevation, does not induce expression of the Hsp70i proteins. Despite constitutive expression of testis-specific Hsp70 proteins, spermatocytes are very sensitive to damage at… CONTINUE READING

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