Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes

@article{Mou2003InducersOP,
  title={Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes},
  author={Zhonglin Mou and W. Fan and X. Dong},
  journal={Cell},
  year={2003},
  volume={113},
  pages={935-944}
}
  • Zhonglin Mou, W. Fan, X. Dong
  • Published 2003
  • Biology, Medicine
  • Cell
    • NPR1 is an essential regulator of plant systemic acquired resistance (SAR), which confers immunity to a broad-spectrum of pathogens. SAR induction results in accumulation of the signal molecule salicylic acid (SA), which induces defense gene expression via activation of NPR1. We found that in an uninduced state, NPR1 is present as an oligomer formed through intermolecular disulfide bonds. Upon SAR induction, a biphasic change in cellular reduction potential occurs, resulting in reduction of… CONTINUE READING
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    References

    SHOWING 1-10 OF 73 REFERENCES
    Nuclear Localization of NPR1 Is Required for Activation of PR Gene Expression
    • 579
    • PDF
    Characterization of an Arabidopsis Mutant That Is Nonresponsive to Inducers of Systemic Acquired Resistance.
    • 1,310
    • PDF
    Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance.
    • 707
    • PDF
    The Arabidopsis NPR1 Gene That Controls Systemic Acquired Resistance Encodes a Novel Protein Containing Ankyrin Repeats
    • 1,284
    • PDF
    Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance.
    • H. Cao, X. Li, X. Dong
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1998
    • 503
    • PDF
    Activation of Host Defense Mechanisms by Elevated Production of H2O2 in Transgenic Plants
    • 251
    • PDF
    Functional analysis of regulatory sequences controlling PR-1 gene expression in Arabidopsis.
    • 346
    Characterization of a salicylic acid-insensitive mutant (sai1) of Arabidopsis thaliana, identified in a selective screen utilizing the SA-inducible expression of the tms2 gene.
    • 500
    • PDF
    Active oxygen species in the induction of plant systemic acquired resistance by salicylic acid.
    • 1,097
    Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene.
    • 589
    • PDF