Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes

  title={Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes},
  author={Zhonglin Mou and W. Fan and X. Dong},
  • Zhonglin Mou, W. Fan, X. Dong
  • Published 2003
  • Biology, Medicine
  • Cell
  • NPR1 is an essential regulator of plant systemic acquired resistance (SAR), which confers immunity to a broad-spectrum of pathogens. SAR induction results in accumulation of the signal molecule salicylic acid (SA), which induces defense gene expression via activation of NPR1. We found that in an uninduced state, NPR1 is present as an oligomer formed through intermolecular disulfide bonds. Upon SAR induction, a biphasic change in cellular reduction potential occurs, resulting in reduction of… CONTINUE READING
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