Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes.

@article{Viveiros2005InducementAR,
  title={Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes.},
  author={Miguel Viveiros and Ana Carolina Assis Jesus and Mafalda Brito and Clara I Leandro and Marta G. Martins and Diane J. Ordway and Ana Maria Molnar and J{\'o}zsef Moln{\'a}r and Leonard Amaral},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 8},
  pages={3578-82}
}
Expression of eight transporter genes of Escherichia coli K-12 and its DeltaacrAB mutant prior to and after induction of both strains to tetracycline resistance and after reversal of induced resistance were analyzed by quantitative reverse transcriptase PCR. All transporter genes were overexpressed after induced resistance with acrF being 80-fold more expressed in the DeltaacrAB tetracycline-induced strain. 

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