Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome.

The recent discovery of induced pluripotent stem cell (iPSC) technology provides an invaluable tool for creating in vitro representations of human genetic conditions. This is particularly relevant for those diseases that lack adequate animal models or where the species comparison is difficult, e.g. imprinting diseases such as the neurogenetic disorder… CONTINUE READING