Induced pluripotent stem cells: the new patient?

  title={Induced pluripotent stem cells: the new patient?},
  author={Milena Bellin and Maria Carolina Marchetto and Fred H. Gage and Christine L. Mummery},
  journal={Nature Reviews Molecular Cell Biology},
Worldwide increases in life expectancy have been paralleled by a greater prevalence of chronic and age-associated disorders, particularly of the cardiovascular, neural and metabolic systems. This has not been met by commensurate development of new drugs and therapies, which is in part owing to the difficulty in modelling human diseases in laboratory assays or experimental animals. Patient-specific induced pluripotent stem (iPS) cells are an emerging paradigm that may address this. Reprogrammed… 

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