Induced pluripotent stem cell consensus genes: implication for the risk of tumorigenesis and cancers in induced pluripotent stem cell therapy.

@article{Zhang2012InducedPS,
  title={Induced pluripotent stem cell consensus genes: implication for the risk of tumorigenesis and cancers in induced pluripotent stem cell therapy.},
  author={Gaochuan Zhang and Bingxue Shang and Ping Yang and Zhifei Cao and Yanyan Pan and Quansheng Zhou},
  journal={Stem cells and development},
  year={2012},
  volume={21 6},
  pages={
          955-64
        }
}
Induced pluripotent stem cells (iPSCs) have recently boomed enthusiasm in stem cell therapy, whereas high potential tumorigenesis of iPSCs has become the biggest obstacle for clinic application and the tumorigenic genes in iPSCs have not been well documented. In this investigation, using tools of bioinformatics, we analyzed the all available datasets regarded to iPSCs from 11 differentiated cell lines and revealed 593 iPSC consensus genes. Notably, of the 593 genes, 209 were expressed in human… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Rab 25 in cancer : a brief update

Kwai W. Cheng
  • Biochemical Society Transactions
  • 2012