Induced mirror symmetry breaking via template-controlled copolymerization: theoretical insights.
@article{Blanco2012InducedMS, title={Induced mirror symmetry breaking via template-controlled copolymerization: theoretical insights.}, author={Celia Blanco and David Hochberg}, journal={Chemical communications}, year={2012}, volume={48 30}, pages={ 3659-61 } }
A chemical equilibrium model of template-controlled copolymerization is presented for describing the outcome of the experimental induced desymmetrization scenarios recently proposed by Lahav and co-workers.
6 Citations
Mechanically Induced Homochirality in Nucleated Enantioselective Polymerization.
- Materials ScienceThe journal of physical chemistry. B
- 2017
The introduction and solve numerically a kinetic rate equation model of nucleated cooperative enantioselective polymerization in closed systems that confirms the model's capacity for absolute asymmetric synthesis, without chiral cross-inhibition and without explicit autocatalysis.
Models for mirror symmetry breaking via β-sheet-controlled copolymerization: (i) mass balance and (ii) probabilistic treatment.
- Materials ScienceThe journal of physical chemistry. B
- 2012
Two complementary theoretical models for template-induced desymmetrization processes leading to multicomponent homochiral copolymers, including a probabilistic treatment based on random polymerization are developed.
Absolute asymmetric synthesis in enantioselective autocatalytic reaction networks: theoretical games, speculations on chemical evolution and perhaps a synthetic option.
- ChemistryChemistry
- 2014
The understanding of network parameters and of the thermodynamic scenarios that may lead to spontaneous mirror symmetry breaking (SMSB) could assist in the development of new methods for asymmetric synthesis and enantioselective polymerizations, and to frame reasonable speculations on the origin of biological homochirality.
Amplification of enantiomeric excess, mirror-image symmetry breaking and kinetic proofreading in Soai reaction models with different oligomeric orders.
- ChemistryPhysical chemistry chemical physics : PCCP
- 2012
A symmetry breaking test was imposed on three prototypical autocatalytic cycle models showing that an increase in the catalytic oligomer size from one to three leads to a higher tolerance to poorer chiral recognition between the diastereoisomers and identifies the greater impact of the diastsereoisomeric energy difference over an imperfect stereoselectivity in the catalysttic step.
Possible chemical and physical scenarios towards biological homochirality.
- BiologyChemical Society reviews
- 2022
Several scenarios will be discussed that are aimed to reflect the different debates about the emergence of BH: extra-terrestrial or terrestrial origin, nature of the mechanisms leading to the propagation and enhancement of the primeval chiral bias, and temporal sequence between chemical homochirality, BH and life emergence.
Thermodynamic analysis and fluorescence imaging of homochiral amino acid-amino acid interactions at the air/water interface.
- Biology, ChemistryJournal of colloid and interface science
- 2013
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