Induced gene mutation and mitotic non-disjunction in A. nidulans.

@article{Gualandi1981InducedGM,
  title={Induced gene mutation and mitotic non-disjunction in A. nidulans.},
  author={Guido Gualandi and Daniela Bellincampi},
  journal={Toxicology letters},
  year={1981},
  volume={9 4},
  pages={389-94}
}
Toxicants of different classes were analysed for capacity to induce gene mutation and mitotic non-disjunction in Aspergillus nidulans, using selective and permissive tests, respectively. Ethanol, Amphotericin B and MIcanozole, all affecting membrane integrity, induced only non-disjunction, emphasizing the röle of the membrane in mitosis. Benomyl and isopropyl-3-chlorophenyl carbamate (CIPC), two pesticides which interfere with spindle system, induced only non-disjunction. Conversely, mitomycin… CONTINUE READING

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