Induced chromosomal exchange directs the segregation of recombinant chromatids in mitosis of Drosophila.

@article{Beumer1998InducedCE,
  title={Induced chromosomal exchange directs the segregation of recombinant chromatids in mitosis of Drosophila.},
  author={Kelly J. Beumer and Sergio Pimpinelli and Kent G. Golic},
  journal={Genetics},
  year={1998},
  volume={150 1},
  pages={173-88}
}
In meiosis, the segregation of chromosomes at the reductional division is accomplished by first linking homologs together. Genetic exchange generates the bivalents that direct regular chromosome segregation. We show that genetic exchange in mitosis also generates bivalents and that these bivalents direct mitotic chromosome segregation. After FLP-mediated homologous recombination in G2 of the cell cycle, recombinant chromatids consistently segregate away from each other (x segregation). This… CONTINUE READING
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