Induced and spontaneous diabetes mellitus and suppression of cell-mediated immunologic responses. Granuloma formation, delayed dermal reactivity and allograft rejection.

@article{Mahmoud1976InducedAS,
  title={Induced and spontaneous diabetes mellitus and suppression of cell-mediated immunologic responses. Granuloma formation, delayed dermal reactivity and allograft rejection.},
  author={Adel A. F. Mahmoud and Harvey M Rodman and M. Alejandra Mandel and Kenneth S. Warren},
  journal={The Journal of clinical investigation},
  year={1976},
  volume={57 2},
  pages={362-7}
}
These investigations delineate the recently described suppression of a form of cellular hypersensitivity in mice with streptozotocin-induced diabetes mellitus using a variety of cell-mediated immunologic responses in animals with several different forms of diabetes. Streptozotocin- and alloxan-induced diabetic mice and db/db genetically determined diabetic mice showed reductions in the areas of inflammation around Schistosoma mansoni eggs injected into the pulmonary vasculature of 68, 70, 77… CONTINUE READING