Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.

@article{Sengupta2018InducedTD,
  title={Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.},
  author={Satarupa Sengupta and Matthew Sobo and Kyungwoo Lee and Shiva Senthil Kumar and Angela R. White and Ilgen Mender and Christine e. Fuller and Lionel M Chow and Maryam Fouladi and Jerry W Shay and Rachid Drissi},
  journal={Molecular cancer therapeutics},
  year={2018},
  volume={17 7},
  pages={
          1504-1514
        }
}
Brain tumors remain the leading cause of cancer-related deaths in children and often are associated with long-term sequelae among survivors of current therapies. Hence, there is an urgent need to identify actionable targets and to develop more effective therapies. Telomerase and telomeres play important roles in cancer, representing attractive therapeutic… CONTINUE READING