Induced Folding in RNA–Protein Recognition: More than a Simple Molecular Handshake

Abstract

shows costabilization of the structure of both partners, When two macromolecules interact, one or both partanalogous to that observed with an a-helical HIV-1 Rev ners often undergo structural rearrangements to estabpeptide-RRE RNA complex (Tan and Frankel, 1994). lish a complementary binding interface. Such induced Induced folding is clearly an important… (More)
DOI: 10.1016/S0092-8674(00)80908-3

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