Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer.

@article{Kikiowo2021InducedFD,
  title={Induced Fit Docking and Automated QSAR Studies Reveal the ER-$\alpha$ Inhibitory Activity of Cannabis sativa in Breast Cancer.},
  author={Babatomiwa Kikiowo and Adewale J Ogunleye and Opeyemi Iwaloye and Taiwo T Ijatuyi and Niyi S Adelakun and Wasiu O Alashe},
  journal={Recent patents on anti-cancer drug discovery},
  year={2021}
}
BACKGROUND Breast Cancer (BC), a common death-causing disease and the deadliest cancer next to lung cancer, is characterized by an abnormal growth of cells in the tissues of the breast. BC chemotherapy is marked by targeting the activities of some receptors such as Estrogen Receptor alpha (ER-α). At present, one of the most commonly used and approved marketed therapeutic drug for BC is tamoxifen. Despite the short term success of tamoxifen usage, its long time treatment has been associated with… 
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