Indonesian medicinal plants. XXIII. Chemical structures of two new migrated pimarane-type diterpenes, neoorthosiphols A and B, and suppressive effects on rat thoracic aorta of chemical constituents isolated from the leaves of Orthosiphon aristatus (Lamiaceae).

  title={Indonesian medicinal plants. XXIII. Chemical structures of two new migrated pimarane-type diterpenes, neoorthosiphols A and B, and suppressive effects on rat thoracic aorta of chemical constituents isolated from the leaves of Orthosiphon aristatus (Lamiaceae).},
  author={Kazuyoshi Ohashi and Takako Bohgaki and Toshiyuki Matsubara and Hirotaka Shibuya},
  journal={Chemical \& pharmaceutical bulletin},
  volume={48 3},
Two novel migrated pimarane-type diterpenes named neoorthosiphols A (1) and B (2) were isolated from the water decoction of the leaves of Orthosiphon aristatus (Lamiaceae), which has been prescribed in Javanese traditional medicine (jamu) for the treatment of hypertension, etc. The absolute chemical structures have been elucidated on the basis of physicochemical properties. It has been found that two migrated pimarane-type diterpenes (1, 2), four isopimarane-type diterpenes (3, 4, 5, 6), three… Expand
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Two Novel Migrated Pimarane-type Diterpenes, Neoorthosiphols A and B, from the Leaves of Orthosiphon aristatus(Lamiaceae)
Two new migrated pimarane-type diterpenes called neoorthosiphols A and B have been isolated from a water decoction of the leaves of Orthosiphon aristatus (Lamiaceae) cultivated in Java, Indonesia.Expand
Colorless plates from ether , mp 194 — 195 ° C , [ a ] D 1 18 . 1 ° ( CHCl 3 , at 21 ° C )