Indomethacin in Bartter's syndrome: does the syndrome represent a state of hyperprostaglandinism?

@article{Donker1977IndomethacinIB,
  title={Indomethacin in Bartter's syndrome: does the syndrome represent a state of hyperprostaglandinism?},
  author={Ab J. M. Donker and Paul E. de Jong and L W van Eps and Jan R. Brentjens and K. F. C. de Bakker and Hieronymus Doorenbos},
  journal={Nephron},
  year={1977},
  volume={19 4},
  pages={200-13}
}
In three patients with Bartter's syndrome, indomethacin administration resulted in the disappearance of the hypokalemic alkalosis and in a normalization of the elevated plasma renin activity. Changes in calcium and phosphate metabolism during indomethacin medication seemed to indicate an increase in reabsorption activity of the renal proximal tubulus. A… CONTINUE READING