Indomethacin for prevention of heterotopic ossification after hip arthroplasty. A randomized comparison between 4 and 8 days of treatment.

@article{Dorn1998IndomethacinFP,
  title={Indomethacin for prevention of heterotopic ossification after hip arthroplasty. A randomized comparison between 4 and 8 days of treatment.},
  author={Ulrich Dorn and Claude Grethen and Harald Effenberger and H Berka and Thomas Ramsauer and T. M. Drekonja},
  journal={Acta orthopaedica Scandinavica},
  year={1998},
  volume={69 2},
  pages={
          107-10
        }
}
In a randomized, parallel group study, we evaluated the efficacy of a 4-day versus an 8-day course of indomethacin (50 mg, 3 times per day), given as prophylaxis against heterotopic ossification after cementless total hip arthroplasty in 209 patients with arthrosis. Patients receiving the prophylaxis for 8 days had less (p = 0.03) severe heterotopic bone formation. 

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