Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection.

Abstract

Control of pathogens by formation of abscesses and granulomas is a major strategy of the innate immune system, especially when effector mechanisms of adaptive immunity are insufficient. We show in human listeriosis that DCs expressing indoleamine 2,3-dioxygenase (IDO), together with macrophages, are major cellular components of suppurative granulomas in… (More)

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@article{Popov2006Indoleamine2D, title={Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection.}, author={Alexey Popov and Zeinab F. Abdullah and Claudia Wickenhauser and Tomo {\vS}ari{\'c} and Julia Driesen and Franz-Georg Hanisch and Eugen Domann and Emma L Raven and Oliver Dehus and Corinna Hermann and Daniela Eggle and Svenja Debey and Trinad Chakraborty and M D Kurt Kroenke and Olaf Utermoehlen and Joachim L. Schultze}, journal={The Journal of clinical investigation}, year={2006}, volume={116 12}, pages={3160-70} }