Indole microbial metabolites: expanding and translating target(s)

Abstract

A central thesis of mechanisms of action of tryptophan and its metabolites in the intestines, have broadly implicated nuclear receptors and other host enzymes. The notion that all indole metabolites, of necessity, have the same degree and predictable interactions with nuclear receptors has clearly been challenged. The existence of receptors that complement… (More)
DOI: 10.18632/oncotarget.19443

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