Indole alkaloid glucosides from the roots of Isatis indigotica

@article{Liu2016IndoleAG,
  title={Indole alkaloid glucosides from the roots of Isatis indigotica},
  author={Yu-feng Liu and Ming-Hua Chen and Sheng Lin and Yu-huan Li and Dan Zhang and Jian-Dong Jiang and Jiangong Shi},
  journal={Journal of Asian Natural Products Research},
  year={2016},
  volume={18},
  pages={1 - 12}
}
Abstract Five new indole alkaloid glucosides named isatindigotindolosides A-E (1–5), along with three known analogs (6–8), were isolated from an aqueous extract of the Isatis indigotica roots. Their structures including the absolute configurations were determined based on comprehensive spectroscopic data analysis, combined with chemical methods and electronic circular dichroism spectra calculations. In the preliminary assays, compounds 1, 6 and 7 showed antiviral activity against influenza… 
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36 Citations

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Diglycosidic indole alkaloid derivatives from an aqueous extract of Isatis indigotica roots
TLDR
Six new indole alkaloid diglycosides named isatigotindolediosides A-F, along with three known analogs, were isolated from an aqueous extract of the Isatis indigotica roots and showed antiviral activity against Coxsackie virus B3.
Indole alkaloid sulfonic acids from an aqueous extract of Isatis indigotica roots and their antiviral activity
Three new indole alkaloid glycosides with unusual structural features from the roots of Isatis indigotica
Isatindolignanoside A, a glucosidic indole-lignan conjugate from an aqueous extract of the Isatis indigotica roots
Bisindole alkaloids with nitric oxide inhibitory activities from an alcohol extract of the Isatis indigotica roots.
Four new indole alkaloids from the roots of Isatis tinctoria
TLDR
Six new indole alkaloids including four new ones, isatisindigoticanine L-N and isatindigoside M, were established on the basis of extensive spectroscopic techniques including NMR, HRESIMS and IR as well as chemical methods.
Indole alkaloid glycosides with a 1′-(phenyl)ethyl unit from Isatis indigotica leaves
C19-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities
New iridoid glycosides from the fruits of Forsythia suspensa and their hepatoprotective activities.
Four undescribed sulfur-containing indole alkaloids with nitric oxide inhibitory activities from Isatis tinctoria L. roots.
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TLDR
Seven new glycosidic bisindole alkaloids, isatindigobisindolosides A–G (1–7), were isolated from an aqueous extract of the Isatis indigotica roots and showed antiviral activity against both the influenza virus A/Hanfang/359/95 (H3N2) and Coxsackie virus B3 with IC50 values of 8.4–100.0 μM.
Antiviral enantiomers of a bisindole alkaloid with a new carbon skeleton from the roots of Isatis indigotica
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TLDR
A pair of enantiomers of an indole alkaloid containing dihydrothiopyran and 1,2,4-thiadiazole rings was isolated from an aqueous extract of the root of Isatis indigotica by extensive spectroscopic analysis.
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TLDR
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