Indole acts as an extracellular cue regulating gene expression in Vibrio cholerae.

@article{Mueller2009IndoleAA,
  title={Indole acts as an extracellular cue regulating gene expression in Vibrio cholerae.},
  author={Ryan S. Mueller and Sinem Beyhan and Simran G. Saini and Fitnat H. Yildiz and Douglas Hoyt Bartlett},
  journal={Journal of bacteriology},
  year={2009},
  volume={191 11},
  pages={3504-16}
}
Indole has been proposed to act as an extracellular signal molecule influencing biofilm formation in a range of bacteria. For this study, the role of indole in Vibrio cholerae biofilm formation was examined. It was shown that indole activates genes involved in vibrio polysaccharide (VPS) production, which is essential for V. cholerae biofilm formation. In addition to activating these genes, it was determined using microarrays that indole influences the expression of many other genes, including… CONTINUE READING